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  Metabolic Activation Therapy   

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 News:   August 23 , 2009 

  Medicare is conducting a National Coverage Analysis for Outpatient Intravenous Insulin.  This class of therapies  includes MAT® treatment.  Further information is available in the Medicare  Tracking Sheet.  

 Comments posted during a public comment period in April 2009 can be seen at  Comments

 

MAT®  treatment, formerly called Metabolic Activation Therapy,  can stabilize, improve and often reverse the complications of severe diabetes.   MAT®  treatment produces a unique metabolic improvement that is not seen with other IV insulin infusions or with the typical subcutaneous insulin pump.  MAT®  treatment as a major addition to the armamentarium of Endocrinologists, especially for treatment of those patients with diabetes whose complications progress despite "good control" and "state of the art" therapy, or patients who have difficulty maintaining intensive insulin therapy due to hypoglycemic reactions. 

Metabolic Industries is the sole commercial agent with the worldwide licensing rights to MAT® treatment (with the exception of  Asia) and MI has unique expertise in providing MAT®  training for physicians and staff.  

          The MAT® treatment was developed in the 1970s by Dr. Thomas T. Aoki while he was a researcher at the Joslin Research Laboratory, affiliated with Harvard Medical School.  This therapy has been described in peer-reviewed medical journals using several different names:  chronic intermittent intravenous insulin therapy (CIIIT), metabolic activation therapy (MAT),  pulsatile therapy, pulse insulin therapy (PIT), pulsatile intravenous insulin therapy (PIVIT) and hepatic activation.  

          MAT® treatment is most effective used in a program tailored to the individual patient by the treating Endocrinologist.  With that in mind, MI offers licenses for MAT® clinics to Endocrinologists and similarly trained health care professionals.  MI also provides training in MAT® treatment, ongoing assistance with MAT® programs , monitoring, and assessments of patient outcomes.  

 

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